Facilities for Student Research

Fresno State offers chemistry students outstanding access to hands-on experience with major instrumentation. This is a partial list of major instrumentation available through the department and college for student research.

Nuclear Magnetic Resonance

• VNMRS 400 MHz (Agilent-Varian) with Oxford magnet: Solution-state, VT with pre-cooling FTS, one-NMR multinuclear probe with PFG and broadband detection.

Infrared Spectroscopy

• Nicolet Avatar FTIR with ATR Attachment
• Nicolet Nexus 470 FTIR

UV-vis Spectroscopy & Fluorescence

• Perkin-Elmer LS50 spectrofluorimeter
• Shimadzu UV-1800 Spectrometer
• HP Diode Array
• Cary 50

Gas Chromatography

• Agilent 7890/5975 Gas Chromatograph – Mass Spectrometer
• Agilent 6890/5973 Gas Chromatograph – Mass Spectrometer
• Varian 3800/Saturn 2100T Gas Chromatograph – Mass Spectrometer
• Agilent 6890 Gas Chromatograph – Flame Ionization Detector
• Agilent 6850 Gas Chromatograph – Flame Ionization Detector

Liquid Chromatography

• Applied Biosystems API 2000 LC/MS/MS
• Shimadzu LC10/RF-10 HPLC system with fluorescence detector
• Agilent 1180 System
• HP 1040/1050 Sytem

Synthetic Equipment

• Rudolph Autopol III Polarimeter
• Solvent Purifier
• CEM (Discovery) Microwave Reactor
• ISCO Auto Purifier
• Labconco Lyophilizer
• Two 6' Dry Boxes

Atomic Spectroscopy

• PE Optima 2000DV ICP Atomic Emission Spectrometer
• Buck Accusys 24 Atomic Absorption Spectrometer
• GBC 902 Atomic Absorption Spectrometer
• Pananalytical XRD and PERT
• Magix Pro X-Ray Fluorescence

Capillary Electrophoresis

• Two Applied Biosystems 310 Genetic Analyzers
• Beckman Coulter P/ACE MDQ Capillary Electrophoresis Unit

Biochemistry Equipment

• Tissue Culture Facility Including ...
• Sorvall RC6 Centrifuge
• Sorvall RC285 Centrifuge
• RT-PCR

Electrochemical Equipment

• CHI660C and 440A potentiostats and spectroelectrochemical systems
• Pine RRDE voltammetric system

Other Major Equipment

• Infrared Analysis Smog Chamber (142 L long path cell with Hanst optics)
• Tisch Environmental Hi-Vol PM2.5 and PUF samplers
• Thermoelectron Model 42C NOx Analyzer and Model 49C Ozone Analyzer
• Olympus BX45 microscope with CCD and Mideo Caseworks 2 Software
• Olympus SZX7 stereo microscopes

Computational Facility

• Two AMD Athlon 4 processor Linux computers
• 13 Node Linux Redhat high performance computing cluster (part of RIMI)
• Gaussian03 (Ab initio quantum chemistry software), Amber 9.0 (Molecular dynamics software), Mestrelab Research (offline NMR data processing), CYANA (NMR structure calculations) and several other open source software for molecular dynamics and statistical applications.
• Several Windows desktop computers for data analysis

RIMI Facility (http://www.fresnostate.edu/rimi/) – NIH funded biomedical research infrastructure

A state-of-the-art shared resource facility is available for the Chemistry Faculty and Student .This facility includes instrumental support in the areas of proteomics, functional genomics, bioinformatics, and microscopy and functional imaging to nurture biomedical research in the Central Valley. Contact: Krish Krishnan (Research Director).

Molecular studies

• J-815 Circular Dichroism Spectrometer (Spectropolarimeter)
• TA Instruments NANO Differential Scanning Calorimeter

Biological Mass Spectrometers:

• Bruker HCT ultra Ion Trap ETD II
• Bruker micrOTOF-Q II ESI-Qq-TOF Mass Spectrometer
• Bruker autoflex II MALDI TOF/TOF Analyzer

HPLCs:

• Bruker Easy-nLC
• Eksigent nanoLC-2D System

Gel Electrophoresis:

• 2D Mini Gel System
• Gel logic 212 pro, Gel documentation System

Functional Imaging:

• 4D Microscopy Imaging
• Confocal Microscopy Imaging     
• Laser Capture Microdissection

Functional Genomics

• Flow cytometer - Attune
• Luminex MagPix
• Pyromark Q24 sequencer training
• q-PCR: Eppendorf RealPlex2

Support Instruments

• -80 freezer
• Eppendorf Mastercycler pro 384PCR System:
  Flexible for running 1D SDS-PAGE/IEF or 2D gel for protein fractionation.
• Lyophilizer