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College of Science and Mathematics

Qiao-Hong Chen

Professor

Chemistry and Biochemistry | 559-278-2103 | Office: Science 1 Room 362

qchen@csufresno.edu

Education

  • Ph.D. Medicinal Chemistry, Sichuan University, China.
  • M.S. Medicinal Chemistry, West China University of Medical Sciences (WCUMS).
  • B.S. Pharmacy, West China University of Medical Sciences (WCUMS).
Website: Chen Research Group

Courses Taught

CHEM 128A Organic Chemistry I
CHEM 128B Organic Chemistry II
CHEM 230 Advanced Organic Chemistry
CHEM 129A Organic Chemistry Laboratory I
CHEM 129B Organic Chemistry Laboratory II
CHEM 280 Seminar in Chemistry
CHEM 240T Bioorganic Principles of Drug Design
and Drug Action
Dr. Qiao-Hong Chen received her PhD degree in Medicinal Chemistry from Sichuan University, China. Appointed as a lecturer in 2001, she was promoted to the position of full professor in 2003 at Sichuan University. She was a CIHR/Rx&D-HRF Postdoctoral Fellow and an AHFMR Postdoctoral Fellow for three years at the University of Alberta in Canada. From August 2006 to June 2012, she worked as a senior research fellow at Virginia Tech in the USA. Dr. Chen started her position at California State University, Fresno, in 2012. She has published 161 peer-reviewed scientific publications, as well as 5 book chapters.
Macrolide-Based Microtubule
Stabilizing Agents

Naturally occurring macrolides have proven to be highly productive lead structures for anticancer drug discovery, with at least seven epothilone-type agents having entered clinical trials in humans ever the last several years. We are working to identify new drug-like macrolides with improved physicochemical and pharmaceutical properties relative to the known naturally occurring microtubule-stabilizing macrolides.

Analogs of Curcumin and Genistein as Anti-Prostate Cancer Agents

The increased risk of prostate cancer in the first generation of Asian men emigrating to the United States suggests a chemopreventive effect of Asian traditional food. Curcumin and genistein have been identified as candidates for prostate cancer prevention and treatment. However, their respective efficacy in clinic has been limited by the poor bioavailability. We are working to engineer more effective analogs of curcumin and genistein for potential clinical use to treat prostate cancer.

Recent Publications (For a complete list of Publications)

  • 161. "Insight into recent advances in degrading androgen receptor for castration-resistant prostate cancer", Qiao-Hong Chen*, Erick Munoz, and Dennis Ashong. Cancers, 16: 663 (2024).
  • 160. "Crosstalk between Microtubule Stabilizing Agents and Prostate Cancer", Qiao-Hong Chen*, Cancers, 15(13): 3308 (2023).
  • 159. "Tricyclic Diterpenoids Selectively Suppress Androgen Receptor-Positive Prostate Cancer Cells", Inderpal Sekhon, Guanglin Chen, Keyara Piri, Seiji Shinkawa, Dennis Ashong, Qiang Zhang, Guangdi Wang, Qiao-Hong Chen*, Molecules, 28(12): 4743 (2023).
  • 158. "Core Structure-Activity Relationship Studies of 5,7,20-O-Trimethylsilybins in Prostate Cancer Cell Models", SitongWu, Guanglin Chen, Eva Y. Chen, Leyla S. Farshidpour, Qiang Zhang, Guangdi Wang, Qiao-Hong Chen*, Pharmaceuticals, 16: 531(2023).
  • 157. "Targeted 19F-tags to detect amino acids in complex mixtures using NMR spectroscopy", Keeton Montgomery, Aya Elhahashy, Guanglin Chen, Qiao-Hong Chen, V.V. Krishnan*, Journal of Fluorine Chemistry, 266: 110084(2023).
  • 156. "Synthesis and Biological Evaluation of Niclosamide PROTACs", Erick Munoz, Guanglin Chen, Ahamed Hossain, Sitong Wu, Esveidy Oceguera, Jasmine Hang, Tong Lee, Qiang Zhang, Guangdi Wang*, Qiao-Hong Chen*, Bioorganic & Medicinal Chemistry Letters, 72: 128870(2022).
  • 155. "5-Substituted 3,3’,4’,7-tetramethoxyflavonoids — a novel class of potent DNA triplex specific binding ligands", Venessa Rangel, Landy Gu, Guanglin Chen, Qiao-Hong Chen, Liang Xue*, Bioorganic & Medicinal Chemistry Letters, 61: 128608 (2022).
  • 154. "3-O-Carbamoyl-5,7,20-O-trimethylsilybins: Synthesis and preliminary antiproliferative evaluation", Sitong Wu, Guanglin Chen, Qiang Zhang, Guangdi Wang, Qiao-Hong Chen*, Molecules, 26 (21): 6421(2021).
  • 153. "Identification of ligand binding sites in intrinsically disordered proteins with a differential binding score", Qiao-Hong Chen and V. V. Krishnan*, Scientific Reports, 11: 22583 (2021).
  • 152. "An amide mimic of desTHPdactylolide: Total synthesis and antiproliferative evaluation", Guanglin Chen, Maricarmen Gonzalez, Ziran Jiang, Qiang Zhang, Guangdi Wang, Qiao-Hong Chen*, Bioorganic & Medicinal Chemistry Letters, 40:127970 (2021).
  • 151. "1-Chromonyl-5-imidazolyl-pentadienone demonstrates anti-cancer action against TNBC and exhibits synergism with paclitaxel", Karan Modi, Scott Lawson, Guanglin Chen, Deepthi Tumuluri, Inga Rekhtman, Michael Kurtz, Gabriela Cristina Brailoiu, Qiao-Hong Chen, Ashakumary Lashmikuttyamma, International Journal of Molecular Sciences, 21(16): 5777 (2020).
  • 150. "Comp34 displays potent preclinical antitumor efficacy in triple-negative breast cancer via inhibition of NUDT3-AS4, a novel oncogenic long noncoding RNA", Qiongyu Hao, Piwen Wang, Pranabananda Dutta, Seyung Chung, Qun Li, Kun Wang, Jieqing Li, Wei Cao, Wenhong Deng, Qing Geng, Katrina Schrode, Magda Shaheen, Ke Wu, Donghui Zhu, Qiao-Hong Chen, Guanglin Chen, Yahya Elshimali, and Jay Vadgama, Yong Wu, Cell Death & Disease, 11(12), 1052 (2020).
  • 149. "Second-generation androgen receptor antagonists as hormonal therapeutics for three forms of prostate cancer", Pravien Rajaram, Alyssa Rivera, Kevin Muthima, Nicholas Olveda, Hubert Muchalski*, and Qiao-Hong Chen*, Molecules, 25(10): 2448 (2020).
  • 148. "23-O-Substituted-2,3-dehydrosilybins selectively suppress androgen receptor-positive LNCaP prostate cancer cell proliferation", Ziran Jiang, Arman Sekhon, Yogeshwari Oka, Guanglin Chen, Nagat Alrubati, Jasleen Kaur, Alexia Orozco, Qiang Zhang, Guangdi Wang, and Qiao-Hong Chen*, Natural Product Communications, 15(5): 1-10 (2020).
  • 147. "New zampanolide mimics: Design, synthesis, and antiproliferative evaluation", Guanglin Chen, Ziran Jiang, Qiang Zhang, Guangdi Wang, and Qiao-Hong Chen*, Molecules, 25(2), 362 (2020).
  • 146. "PP2Cδ inhibits p300-mediated p53 acetylation via ATM/BRCA1 pathway to impede DNA damage response in breast cancer", Qun Li, Qiongyu Hao, Wei Cao, Jieqing Li, Ke Wu, Yahya Elshimali, Donghui Zhu, Roshni Iyer, Kytai Truong Nguyen, Qiao-Hong Chen, Guanglin Chen, Jay Vadgama, Yong Wu, Science Advances, 5(10): eaaw8417 (2019).
  • 145. "Immune modulation of Asian folk herbal medicines and related chemical components for cancer management", Manee Patanapongpibul and Qiao-Hong Chen*, Current Medicinal Chemistry, 26(17): 3042-3067 (2019).
  • 144. "A novel curcumin analog inhibits canonical and non-canonical functions of telomerase through STAT3 and NF-kB inactivation in colorectal cancer cells", Seyung Chung, Pranabananda Dutta, Nathaniel Chard, Yong Wu, Qiao-Hong Chen, Guanglin Chen, Jaydutt Vadgama, Oncotarget, 10: 4516-4531 (2019).
  • 143. "Synthesis and antiproliferative evaluation of new zampanolide mimics", Guanglin Chen, Manee Patanapongpibul, Ziran Jiang, Qiang Zhang, Shilong Zheng, Guangdi Wang, James D. White, Qiao-Hong Chen*, Organic & Biomolecular Chemistry, 17: 3830-3844, Supplementary information (2019).
  • 142. "Tageting of PP2Cδ by a small molecule C23 inhibits high glucose-induced breast cancer progression in vivo", Ke Wu, Xiaoting Yu, Zhimin Huang, Donghui Zhu, Xianghua Yi, Ying-Li Wu, Qiongyu Hao, Kevin T. Kemp II, Yahya Elshimali, Roshni Lyer, Kytai Truong Nguyen, Shilong Zheng, Guanglin Chen, Qiao-Hong Chen, Guangdi Wang, Jaydutt V Vadgama, Yong Wu, Antioxidant and Redox Signaling, 30(17):1983-1998 (2019).
  • 141. "Mosquito Acetylcholinesterase as a Target for Novel Phenyl-Substituted Carbamates", James M. Mutunga, Ming Ma, Qiao-Hong Chen, Joshua A. Hartsel, Dawn M. Wong, Sha Ding, Max Totrov, Paul R. Carlier and Jeffrey R. Bloomquist, International Journal of Environmental Research and Public Health, 16(9), 1500; https://doi.org/10.3390/ijerph16091500 (2019).
  • 140. "Nitrogen-containing derivatives of tetramethylquercetin: synthesis and biological profiles in prostate cancer cell models", Pravien Rajaram, Ziran Jiang, Guanglin Chen, Alyssa Rivera, Alison Phasakda, Qiang Zhang, Shilong Zheng, Guangdi Wang, and Qiao-Hong Chen*, Bioorganic Chemistry, 87: 227-239 (2019).
  • 139. "O-Aminoalkyl-O-trimethyl-2,3-dehydrosilybins: Synthesis and in vitro effects towards prostate cancer cells", Bao Vue, Sheng Zhang, Andre Vignau, Guanglin Chen, Xiaojie Zhang, William Diaz, Qiang Zhang, Shilong Zheng, Guangdi Wang, and Qiao-Hong Chen*, Molecules, 23: 3142 (2018).
  • 138. "Structure-activity relationship and pharmacokinetic studies of 3-O-substitutedflavonols as anti-prostate cancer agents", Xiang Li, Changde Zhang, Shanchun Guo, Pravien Rajaram, Maizie Lee, Guanglin Chen, Ryan Fong, Aaron Gonzalez, Qiang Zhang, Shilong Zheng, Guangdi Wang, and Qiao-Hong Chen*, European Journal of Medicinal Chemistry, 157: 978-993 (2018).
  • 137. "Optimization of diarylpentadienones as chemotherapeutics for prostate cancer", Manee Patanapongpibul, Changde Zhang, Guanglin Chen, Shanchun Guo, Qiang Zhang, Shilong Zheng, Guangdi Wang, and Qiao-Hong Chen*, Bioorganic & Medicinal Chemistry, 26(16): 4751-4760 (2018).
  • 136. "Optimized synthesis and antiproliferative activity of desTHPdactylolides", Guanglin Chen, Rubing Wang, Bao Vue, Manee Patanapongpibul, Qiang Zhang, Shilong Zheng, Guangdi Wang, James D. White, and Qiao-Hong Chen*, Bioorganic & Medicinal Chemistry, 26(12): 3514-3520,  Supplementary data (2018).
  • 135. "Select β- and ɣ-branched 1-alkylpyrazol-4-yl methylcarbamates exhibit high selectivity for inhibition of Anopheles gambiae versus human acetylcholinesterase", Paul R. Carlier, Qiao-Hong Chen, Astha Verma, Dawn M. Wong, James M. Mutunga, Jasmin Mullerm, Rafique Islam, Alex M. Shimozono, Fan Tong, Jianyong Li, Max Totrov, Jeffrey R. Bloomquist, Pesticide Biochemistry and Physiology, 151: 32-39 (2018).
  • 134. "5- or/and 20-O-Alkyl-2,3-dehydrosilybins: Synthesis and biological profiles on prostate cancer cell models", Bao Vue, Xiaojie Zhang, Timmy Lee, Nandini Nair, Sheng Zhang, Guanglin Chen, Qiang Zhang, Shilong Zheng, Guangdi Wang, Qiao-Hong Chen*, Bioorganic & Medicinal Chemistry, 25(17): 4845-4854 (2017).
  • 133. "3-O-Substituted-3',4',5'-trimethoxyflavonols: synthesis and cell-based evaluation as anti-prostate cancer agents", Xiang Li, Maizie Lee, Guanglin Chen, Qiang Zhang, Shilong Zheng, Guangdi Wang, Qiao-Hong Chen*, Bioorganic & Medicinal Chemistry, 25(17): 4768-4777 (2017).
  • 132. "Asymmetric 1,5-diarylpenta-1,4-dien-3-ones: antiproliferative activity in prostate epithelial cell models and pharmacokinetic studies", Xiaojie Zhang, Shanchun Guo, Chengsheng Chen, German Ruiz Perez, Changde Zhang, Manee Patanapongpibul, Nithya Subrahmanyam, Rubing Wang, Joshua Keith, Guanglin Chen, Yan Dong, Qiang Zhang, Qiu Zhong, Shilong Zheng, Guangdi Wang, and Qiao-Hong Chen*, European Journal of Medicinal Chemistry, 137: 263-279 (2017).
  • 131. "Structure-activity relationship studies of 1,7-diheteroarylhepta-1,4,6-trien-3-ones with two different terminal rings in prostate epithelial cell models", Rubing Wang, Xiaojie Zhang, Chengsheng Chen, Guanglin Chen, Cristian Sarabia, Qiang Zhang, Shilong Zheng, Guangdi Wang, and Qiao-Hong Chen*, European Journal of Medicinal Chemistry, 133: 208-226 (2017).
  • 130. "The Potential of Flavonolignans in Prostate Cancer Management", Bao Vue and Qiao-Hong Chen*, Current Medicinal Chemistry, 23(34): 3925-3950 (2016).
  • 129. "Design, Synthesis, and Biological Evaluation of 1,9-Diheteroarylnona-1,3,6,8-tetraen-5-ones as a New Class of Anti-Prostate Cancer Agents", Xiaojie Zhang, Rubing Wang, German R Perez, Guanglin Chen, Qiang Zhang, Shilong Zheng, Guangdi Wang, and Qiao-Hong Chen*, Bioorganic & Medicinal Chemistry, 24(19): 4692-4700 (2016).
  • 128. "A new class of flavonol-based anti-prostate cancer agents: design, synthesis, and evaluation in cell models", Xiang Li, Guanglin Chen, Xiaojie Zhang, Qiang Zhang,  Shilong Zheng, Guangdi Wang, and Qiao-Hong Chen*, Bioorganic & Medicinal Chemistry Letters, 26(17): 4241-4245 (2016).
  • 127. "Bivalent Carbamates as Novel Control Agents of the Malaria Mosquito, Anopheles gambiae", James M. Mutunga, Qiao-Hong Chen, Dawn M Wong, Henrique Polo, Jianyong Li, Maxim M. Totrov, Aaron D Gross, Paul R. Carlier, Jeffrey R. Bloomquist, CHIMIA International Journal for Chemistry, 70(10): 704-708 (2016).
  • 126. "3-O-Alkyl-2,3-Dehydrosilibinins: Two Synthetic Approaches and in vitro Effects toward Prostate Cancer Cells", Sheng Zhang, Bao Vue, Michael Huang, Xiaojie Zhang, Timmy Lee, Guanglin Chen, Qiang Zhang, Shilong Zheng, Guangdi Wang, and Qiao-Hong Chen*, Bioorganic & Medicinal Chemistry Letters, 26(14): 3226-3231 (2016).
  • 125. "Aerobic Decomposition of Trialkylquercetins: Structure Characterization and Antiproliferative Effect", Sami M.R.Al-Jabban, Xiaojie Zhang, Guanglin Chen, Liva Harinantenaina Rakotondraibe, and Qiao-Hong Chen*, Natural Product Communications, 11: 465-468 (2016).
  • 124. "Synthesis and evaluation of 1,7-diheteroarylhepta-1,4,6-trien-3-ones as curcumin-based anti-cancer agents", Rubing Wang, Xiaojie Zhang, Chengsheng Chen, Guanglin Chen, Qiu Zhong, Qiang Zhang, Shilong Zheng, Guangdi Wang, and Qiao-Hong Chen*, European Journal of Medicinal Chemistry, 110: 164-180 (2016).
  • 123. "Flavonoids with therapeutic potential in prostate cancer", Bao Vue, Sheng Zhang, and Qiao-Hong Chen*, Anti-Cancer Agents in Medicinal Chemistry, 16(10): 1205-1229 (2016).
  • 122. "Silibinin Derivatives as Anti-Prostate Cancer Agents: Synthesis and Cell-Based Evaluations", Bao Vue, Sheng Zhang, Xiaojie Zhang, Konstantinos Parisis, Qiang Zhang, Shilong Zheng, Guangdi Wang, and Qiao-Hong Chen*, European Journal of Medicinal Chemistry, 109: 36-46 (2016).
  • 121. "Epoxide Opening of a 7,17-Seco-7,8-Epoxy-C19-Diterpenoid Alkaloid", Hong Ji, Feng-Peng Wang* and Qiao-Hong Chen*, Natural Product Communications, 10: 2071-2074 (2015).
  • 120. "Synergistic Effects of Dietary Natural Products as Anti-Prostate Cancer Agents", Bao Vue, Sheng Zhang and Qiao-Hong Chen*, Natural Product Communications, 10: 2179-2188 (2015).
  • 119. "Further Studies on Structure-Cardiac Activity Relationships of Diterpenoid Alkaloids", Zhong-Tang Zhang, Xi-Xian Jian, Jia-Yu Ding, Hong-Ying Deng, Ruo-Bing Chao*, Qiao-Hong Chen*, Dong-Lin Chen and Feng-Peng Wang*, Natural Product Communications, 10: 2075-2084 (2015).
  • 118. "Synthesis and Anti-Proliferative Effects of Quercetin Derivatives", Sami M.R. Al-Jabban, Xiaojie Zhang, Guanglin Chen, Ermias Addo Mekuria, Liva Harinantenaina Rakotondraibe, and Qiao-Hong Chen*, Natural Product Communications, 10: 2113-2118 (2015).
  • 117. "A new class of hybrid anticancer agents inspired by the synergistic effects of curcumin and genistein: design, synthesis, and anti-proliferative evaluation", Qiao-Hong Chen*, Kevin Yu, Xiaojie Zhang, Guanglin Chen, Andrew Hoover, Francisco Leon, Rubing Wang, Nithya Subrahmanyam, Ermias A Mekuria, Liva H Rakotondraibe, Bioorganic & Medicinal Chemistry Letters, 25(20): 4553-4556 (2015).
  • 116. "Effects of curcumin-based compounds on proliferation and cell death in cervical cancer cells", Xiaojie Zhang, Rubing Wang, Guanglin Chen, Laurent Dejean*, and Qiao-Hong Chen*, Anticancer Research, 35(10): 5293-5298 (2015).
  • 115. "Structure-Activity relationship and pharmacokinetic studies of 1,5-diheteroarylpenta-1,4-dien-3-ones: a class of promising curcumin-based anti-cancer agents", Rubing Wang, Chengsheng Chen, Xiaojie Zhang, Changde Zhang, Qiu Zhong, Guanglin Chen, Qiang Zhang, Shilong Zheng, Guangdi Wang, and Qiao-Hong Chen*, Journal of Medicinal Chemistry, 58 (11), 4713–4726 (2015).
  • 114. Design, Synthesis, and Evaluation of Genistein Analogues as Anti-cancer Agents", Pahoua Xiong, Rubing Wang, Xiaojie Zhang, Eduardo Dela Torre, Francisco Leon, Qiang Zhang, Shilong Zheng, Guangdi Wang, and Qiao-Hong Chen*, Anti-Cancer Agents in Medicinal Chemistry, 15(9): 1197-1203 (2015).
  • 113. "Curcumin-Based Anti-Prostate Cancer Agents", Qiao-Hong Chen*, Anti-Cancer Agents in Medicinal Chemistry, 2: 138-156 (2015).
  • 112. "Stemona Alkaloids: Biosynthesis, Classification, and Biogenetic Relationships", Feng-Peng Wang* and Qiao-Hong Chen*, Natural Product Communications, 9: 1809-1822 (2014).
  • 111. "Acetylcholinesterase of the sand fly, Phlebotomus papatasi (Scopoli): construction, expression and biochemical properties of the G119S orthologous mutant", Kevin B Temeyer*, Fan Tong, Maxim M Totrov, Alexander P Tuckow, Qiao-Hong Chen, Paul R Carlier, Adalberto A Pérez de León, Jeffrey R Bloomquist, Parasites & Vectors, 7: 577 (2014).
  • 110. "Zampanolide and Dactylolide: Cytotoxic Tubulin-Assembly Agents and Promising Anticancer Leads", Qiao-Hong Chen* and David G. I. Kingston*, Natural Product Reports, 31: 1202-1226 (2014).
  • 109. "Ring A Conformation of Aconine and Pseudaconine in CDCl3", Hong-Ying Deng, Qiao-Hong Chen*, and Feng-Peng Wang*, Natural Product Communications, 9: 785-786 (2014).
  • 108. "Total Synthesis of Fuzinoside", Ping He, Xiao-Huan Li, Qiao-Hong Chen*, Jin-Song Yang, Feng-Peng Wang*, Tetrahedron, 70: 4022-4030 (2014).
  • 107. "New C20-Diterpenoid Alkaloids from Delphinium laxicymosum var
    pilostachyum", Dong-Lin Chen, Ping Tang, Qiao-Hong Chen*, and Feng-Peng Wang*, Natural Product Communications, 9(5): 623-625 (2014).
  • 106. "Design, synthesis, and evaluation of novel heteroaromatic analogs of curcumin as anti-cancer agents", Nawras Samaan, Qiu Zhong, Jayjoel Fermandez, Guanglin Chen, Ali M Hussain, Shilong Zheng, Guangdi Wang, and Qiao-Hong Chen*, European Journal of Medicinal Chemistry, 75: 123-131 (2014).
  • 105. "Further revisions on the diterpenoid alkaloids reported in a JNP paper (2012, 75, 1145-1159)", Feng-Peng Wang, Dong-Lin Chen, Hong-Ying Deng, Qiao-Hong Chen, Xiao-Yu Liu, and Xi-Xian Jian, Tetrahedron, 70: 2582-2590 (2014).


BOOKS AND CHAPTERS

  • 1. "The C19-Diterpenoid Alkaloids" The Alkaloids, Chemistry and Biology, Feng-Peng Wang and Qiao-Hong Chen, Elsevier Press, Vol. 69, 1-577 (2010).
  • 2. "The C18-Diterpenoid Alkaloids" (Chapter 1), The Alkaloids: Chemistry and Biology, Feng-Peng Wang, Qiao-Hong Chen, and Xiao-Tian Liang, Elsevier Press, Vol. 67, 1-79 (2009).
  • 3. "Chapter 9 Quinones", Current Natural Products Chemistry, Qiao-Hong Chen, Ed. Feng-Peng Wang, Science Press, Beijing, 253-264 (2009) (book chapter, in Chinese).
  • 4. "Chapter 8 Phenylpropanoids", Current Natural Products Chemistry, Qiao-Hong Chen, Ed. Feng-Peng Wang, Ed. Feng-Peng Wang, Science Press, Beijing, 221-252 (2009) (book chapter, in Chinese).
  • 5. "Recent advances in the second-generation taxoids", Progress in Medicinal Chemistry, Qiao-Hong Chen, and Feng-Peng Wang, Ed. Si-Xun Peng. Chemical Industry Press, Beijing, 4: 89-107 (2005) (book chapter, in Chinese).


Edited Books


Recent US Patent

  • ''Therapeutic Uses of Curcumin Analogs for Treatment of Prostate Cancer", Qiao-Hong Chen, United States Patent (2016), pp36, US 9,499,529 B2.

 


ACADEMIC HONORS OR AWARDS

  • 2017 - 2018 Provost’s Award for Research, Scholarship and Creative Accomplishment, Fresno State.
  • 2015 - 2016 College of Science and Mathematics Outstanding Faculty Research Award.
  • 2014 A research project entitled "Systematic Studies on Chemical Constituents of Traditional Chinese Medicines 'Cao Wu'," carried out by Feng-Peng Wang, Qiao-Hong Chen, et. al, received the Natural Science Award from the Ministry of Education in China (First Place).
  • 2013 - 2014 Provost’s Promising New Faculty Award, Fresno State.
  • 2004 - 2006 Canada's Research-Based Pharmaceutical Companies Health Research Foundation (Rx&D-HRF) and Canadian Institutes of Health Research (CIHR) Post-Doctoral Fellowship in Pharmacy, Canada.
  • 2004 - 2006 Alberta Heritage Foundation for Medical Research (AHFMR) Post-Doctoral Fellowship (incentive award), Canada.
  • 2003 - 2004 Alberta Heritage Foundation for Medical Research (AHFMR) Fast-track Post-Doctoral Fellowship, Canada.
  • 2003 Award for Top 100 National Excellent Doctoral Dissertations in 2003, from the National Evaluation Institute of Degrees and Grade Education, of the Ministry of Education in China; the only honoree in the Medicinal Chemistry category of the year.
  • 2003 Award for outstanding Doctoral Dissertations (as one of two honorees), Sichuan University, China.
  • 2002 A research project "Studies on Chemical Constituents of Traditional Chinese Medicines 'Cao Wu'," carried out with Feng-Peng Wang, Qiao-Hong Chen, et. al, received the Natural Science Award from the Ministry of Education in China (First Place).
  • 2002 Outstanding Young Teacher Award, Sichuan University, China.
  • 2000 Excellent Graduate Leadership, Sichuan University, China.
  • 2000 Excellent Graduate Studentship, Sichuan University, China.
  • 1997 Excellent Graduate Studentship, West China University of Medical Sciences, China.