Teresa Brooks

My primary interests lie in developing research tools to investigate the interactions between proteins involved in disease.  I began with my Masters work where I developed a transgenic potato that expressed an antimicrobial peptide.  My background in Biochemistry and Microbiology has given a broad tool set that can be applied to a variety of host-pathogen studies, including the antibody-antigen interaction work of the Brooks lab. Of significant note is the role I played in reference 1a (King et al., 2018) in which I developed the Listeria invasion assay to assess the efficacy of sing chain antibodies to prevent infection.

My current involvement has primarily been involving cell culture systems for the production of monoclonal and recombinant antibodies.  For my publication listed as 1b (Mohavedin et al. 2017) my chief contribution was the cultivation of the hybridoma in bioreactor flasks and purification of the antibody for structural studies.  More recently, my work has focused on the development of CHO cell lines to express recombinant antibodies and human-like antigens such as the cancer-specific markers of MUC1 and MUC16.