My primary interests lie in developing research tools to investigate the interactions
between proteins involved in disease.I began with my Masters work where I developed a transgenic potato that expressed
an antimicrobial peptide.My background in Biochemistry and Microbiology has given a broad tool set that can
be applied to a variety of host-pathogen studies, including the antibody-antigen interaction
work of the Brooks lab. Of significant note is the role I played in reference 1a (King
et al., 2018) in which I developed theListeriainvasion assay to assess the efficacy of sing chain antibodies to prevent infection.
My current involvement has primarily been involving cell culture systems for the production
of monoclonal and recombinant antibodies.For my publication listed as 1b (Mohavedin et al. 2017) my chief contribution was
the cultivation of the hybridoma in bioreactor flasks and purification of the antibody
for structural studies.More recently, my work has focused on the development of CHO cell lines to express
recombinant antibodies and human-like antigens such as the cancer-specific markers
of MUC1 and MUC16.